The Prince of Wales and his two sons will mix with TV royalty at the premiere of a flagship Netflix series on Thursday evening.
Sir David Attenborough will host the event for the global launch of upcoming series Our Planet.
The naturalist made the move to Netflix for the eight-part series, which will carry an overtly environmental message exploring the natural world and how to protect it.
Charles, president of WWF-UK, will attend the premiere at the Natural History Museum in London along with William and Harry.
The younger royals have attended numerous events supporting conservation, and Harry recently helped schoolchildren plant trees.
Speaking to the BBC Science Focus magazine, Sir David said ahead of the new series: “You, me and the rest of the human species are critically dependent on the health of the natural world.
“If the seas stop producing oxygen, we would be unable to breathe, and there is no food that we can digest that doesn’t originate from the natural world.
“If we damage the natural world, we damage ourselves.”
Netflix has also announced the series will feature local narrators in 10 languages, including actresses Penelope Cruz and Salma Hayek, who will narrate for Spain and Latin America respectively.