Oil giant Shell confirmed that some of the 475 jobs being cut in its UK and Ireland operations will be at Mossmorran in Fife.
It could not comment on the number or nature of the posts to go, saying details have still to be worked out.
The majority of the 475 jobs will be in the Aberdeen area, with the St Fergus plant in Aberdeenshire also affected.
The Scottish jobs are part of the 2,200 jobs being cut by Shell worldwide, bringing the total number of staff and direct contractor roles cut by Shell since the start of last year to 12,500.
Paul Goodfellow, Shell vice president for UK and Ireland, blamed the challenging market conditions for the move.
The Mossmorran plant is shared by Shell and ExxonMobil and employs about 200 people.
Shell UK operates the Fife Natural Gas Liquids (FNGL) Fractionation Plant that extracts natural gasoline, ethane, propane and butane from natural gas liquids pumped from the St Fergus gas plant at Peterhead.
Ethane is forwarded to the adjacent ExxonMobil Chemical Limited Fife Ethylene Plant (FEP) where it is converted into ethylene by steam cracking.
The products from both sites are transported by pipeline or road tanker.
They mostly go to the Shell UK and ExxonMobil Braefoot Bay marine terminal on the Firth of Forth near Aberdour in Fife to be shipped.
Some of the ethylene produced is distributed via the UK ethylene pipeline to other manufacturing plants in the UK.
