A diversion was in place via Perth Road and Hawkhill.
But Scottish Water confirmed on Friday afternoon that the works have now been cleared and the road reopened.
A spokesperson for Scottish Water said: “Following the completion of road reinstatement at Riverside Drive, the eastbound carriageway has reopened to traffic this afternoon and the diversion signage that has been in place over the last week is being removed.
“We would like to thank the local community and road users for their patience and understanding while our team was working to repair the sewer and get the road reopened as quickly as possible.”