A section of the A92 between Lochgelly and Cowdenbeath was blocked in both directions following a two-vehicle crash on Tuesday night.
Emergency services rushed to the scene on the A92 northbound at around 7.15pm following reports of the collision.
Both the northbound and eastbound carriageways were restricted for several hours as a result, with road users in the area warned to take care.
The road has now reopened.
A Police Scotland spokesperson said: “Emergency services are in attendance following a two-vehicle crash on the A92 northbound near Lochgelly which was reported around 7.15pm on Tuesday.”
Reports on social media suggest at least one ambulance is on the scene, although the extent of any injuries sustained is unknown.