The A84 has been blocked following a two-vehicle crash near Doune.
The crash happened at around 3.10pm just south of the River Teith.
It is believed that the vehicles collided head on.
A spokesman for Police Scotland said the crash was on a bend and that the Scottish Ambulance Service had been asked to attend.
*UPDATE* #A84 South of Doune closed b/d due to RTC
Div:
N/B #A820 towards Dunblane
S/B #A873 towards Blair DrummondNot suitable 4 HGV's
— Traffic Scotland (@trafficscotland) July 27, 2016
The extent of any injuries is not yet known.
Police are currently diverting traffic along the A820 and the A873.